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What to do if…
you develop a new severe headache with nausea after a recent infection
Short answer
Treat a new severe headache with nausea after a recent infection as urgent: get same-day medical assessment. If it’s sudden/“worst ever” or you have any danger signs, call 999 or go to A&E now.
Do not do these things
- Do not “sleep it off” if the headache is new and severe, getting worse, or comes with vomiting.
- Do not drive yourself to A&E if you feel very unwell, drowsy, faint, or your symptoms are severe.
- Do not keep taking extra painkillers to “push through” if the pain is severe or different from your usual headaches.
- Do not accidentally double-dose paracetamol by mixing cold/flu products with separate paracetamol (many combination medicines already contain it).
- Do not ignore signs of serious illness (for example fever, a rash that doesn’t fade, confusion, stiff neck, or new weakness) because you “just had a cold/flu”.
- Do not go back to work/college or stay alone if you’re deteriorating or struggling to think clearly.
What to do now
- Check for “call 999 / go to A&E now” signs. Do this quickly and act if any apply:
- Sudden, extremely severe headache (especially if it came on quickly or is the worst you’ve ever had).
- Confusion, new drowsiness, collapse, seizure, or you’re hard to wake.
- New weakness, facial droop, speech problems, severe unsteadiness, or new vision problems.
- Severe headache with fever, stiff neck, dislike of bright lights, or repeated vomiting.
- A new rash that does not fade when pressed (or unexplained purple/red spots).
- Severe headache after a recent head injury, even a few days later.
- If you’re not in the “999/A&E now” group, still seek same-day help.
- Use NHS 111 (call 111, 111 online, or the NHS App) and say: “New severe headache with nausea/vomiting after a recent infection” and whether it’s getting worse.
- If your symptoms worsen while you’re trying to get help, re-check step 1 and escalate to 999/A&E if any danger signs appear.
- Don’t stay alone. Ask someone to stay with you (or be reachable) for the next few hours in case you become more unwell, confused, or faint.
- Write down a 60-second timeline for the clinician. Note:
- When the infection started and what it was (respiratory, sinus, ear, throat, stomach, etc.).
- Exactly when the headache started, how fast it peaked, where it is, and what makes it worse.
- Whether you have fever, neck stiffness, light sensitivity, rash, confusion, new neurological symptoms, or persistent vomiting.
- Keep things safe while you arrange help.
- Sip water if you can keep fluids down; stop if you’re repeatedly vomiting.
- Avoid alcohol and recreational drugs.
- If you take regular medicines, keep the packets with you; don’t start antibiotics you have “left over”.
What can wait
- You do not need to decide what the diagnosis is right now (migraine vs. meningitis vs. something else).
- You do not need to research every possible cause online.
- You do not need to “prove” it’s serious before you seek help—new severe headache + nausea after infection is enough to get assessed today.
Important reassurance
It’s common to feel frightened and unsure when a headache is severe and different from normal—especially after an infection. Getting checked urgently is not overreacting; it’s the safest way to rule out the small number of serious causes that need fast treatment.
Scope note
These are first steps to keep you safe and get you assessed quickly. Further tests and treatment depend on what clinicians find.
Important note
This is general information, not a diagnosis or a substitute for medical care. If symptoms are severe, sudden, worsening, or you’re worried, seek urgent help.
Additional Resources
- https://www.nhs.uk/symptoms/headaches/
- https://www.nhs.uk/conditions/meningitis/symptoms/
- https://www.nhs.uk/conditions/meningitis/
- https://www.nhs.uk/nhs-services/urgent-and-emergency-care-services/when-to-call-999/
- https://www.nhs.uk/nhs-services/urgent-and-emergency-care-services/when-to-use-111/
- https://ukhsa.blog.gov.uk/2025/10/31/what-is-meningitis-symptoms-risks-and-how-to-protect-yourself/